ASCO 2026 Conference Review – Lung Cancer
In this review:
– LIBRETTO-432: adjuvant selpercatinib in stage IB-IIIA RET fusion-positive NSCLC
– HARMONi-6: chemotherapy + ivonescimab vs. tislelizumab in squamous NSCLC
– CROWN: lorlatinib vs. crizotinib in ALK+ NSCLC
– WU-KONG28: sunvozertinib vs. chemotherapy in NSCLC with EGFR exon20ins
– OptiTROP-Lung05: sacituzumab tirumotecan ± pembrolizumab in PD-L1+ NSCLC
– FLAME: osimertinib ± chemotherapy in persistent ctDNA EGFR-altered NSCLC after osimertinib monotherapy
– LORIN: neoadjuvant lorlatinib in stage 3 ALK-fusion NSCLC
– TRITON: tremelimumab + durvalumab + chemotherapy vs. pembrolizumab + chemotherapy in STK11/KEAP1/KRAS-altered NSCLC
– ALCHEMIST EA5142: adjuvant nivolumab after standard adjuvant therapy in resected NSCLC
– NIBIT-EPI-MESO: tumour methylation subtypes in pleural mesothelioma
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